A scientific team headed by Prof. Philippe Karoyan from Sorbonne University (Biomolecules Laboratory, UMR7203), supported by SATT Lutech, has developed a lure able to block the SARSCoV-2 virus and preventing it from infecting pulmonary cells. In short, the virus has a protein on its surface called SPIKE. This protein is a key that interacts with a human lock called hACE2. The team developed a mime of this lock and demonstrated that this lure irreversibly blocked the key of the virus. This lure does not exhibit any toxicity even at high doses on human lung cells. This tool could be used prophylactically at first, in prevention, for example formulated in the form of sublingual tablets. This discovery shows that French researchers are capable of innovating and offering alternative solutions to vaccines. A manuscript submitted for publication is also available in preprint format on the bioRχiv website via the following link:A patent has been filed and licensed to the Start-up χ-Pharma, supported by SATT Lutech.