Percutaneous mitral valve repair implant
A cardiovascular implant to be inserted percutaneously for the repair of the mitral valve
- Mitral regurgitation
- Mitral valve
- Heart valve
- Medical device
Nowadays, 2 to 3% of the world population suffer from mitral regurgitation. In the United States and Europe, nearly 2.3 million patients suffer from severe mitral regurgitation. Mitral valve pathologies affect around 9% of people over 75 years of age, and the incidence is bound to increase with the aging of the population. Each year, nearly 500,000 new patients are diagnosed with this disease, but more than 80% are not treated because the stage of the disease is too advanced for them to survive surgery, and there is a lack of percutaneous devices available. Mitral insufficiency can be treated with medication and surgery, and since recent years, thanks to transcatheter devices. However, there are currently very few minimally invasive repair devices on the market.
The innovation is a cardiovascular implant to be inserted percutaneously for the repair of the mitral valve. It aims at filling the space between the two leaflets, by fixing a balloon with an adjustable volume on one of the leaflets (preferentially the posterior leaflet).
A model of the implant has been produced, and tests have been made in vitro on a defective biological valve for a proof of concept. A computer simulation for the analysis of the evolution of the implant is being conducted. A new project is currently being investigated, with the inflatable balloon being replaced by another system. A patent application has been filed.
- Device for the repair of heart valve, specially designed for the treatment of mitral regurgitation (percutaneously)
- The project was developed as part of a collaboration between KOL in thoracic and cardiovascular surgery and a research team from the University of Compiègne, France
- It opens a treatment of mitral regurgitation for patients who cannot undergo an invasive surgical procedure
- Percutaneous treatment decreases the patient’s hospital stay. A chirurgical replacement will still be possible for theses patients
- Reduction of an operative risk via a minimally invasive operation
- No pre-operative preparation: the device is delivered ready for use (and can be introduced through a catheter), contrary to the other devices which require an average of 30 minutes of preparation
- A patent (FR1858233) has been filed in 2018 (PCT in September 2019) and the report received in July 2019 indicates that the invention is considered new, inventive and industrially applicable.
HEALTH | Number ref.: #MA00469
Mitral regurgitation, Mitral valve, Percutaneous, Implant, Heart valve, Medical device