Summary
Karim Ghoufiri
Business developper
Technology
- One of the mechanisms of antibiotic resistance is the formation of a biofilm that protects bacteria.
- The aim of the invention is to facilitate the passage of antibiotics without destroying the biofilm by applying ultrasound.
Bacterial colonies with (A) and without ultrasound (B)
Market
- This approach could help combat nosocomial infections, particularly after the placement of implants such as hip or knee replacements. In 8% of implant surgeries, bacteria form a biofilm; currently, the only alternative is to remove the implant and wait several months before placing a new one. With this invention, it would be possible to treat the biofilm.
- Biofilms are thought to be responsible for 65% to 75% of nosocomial infections.
Development status
- TRL 3 (successful PoC on a biofilm model (E. Coli) in an alginate gel)
IP
- PCT patent application filed on December 20, 2024.
Valorisation strategy
- Co-development